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Lorem ipsum dolor sit amet, consectetur adipiscing elit id venenatis pretium risus euismod dictum egestas orci netus feugiat ut eestas ut sagittis tincidunt phasellus elit etiam cursus orci in. Id sed montes.
Lorem ipsum dolor sit amet, consectetur adipiscing elit id venenatis pretium risus euismod dictum egestas orci netus feugiat ut eestas ut sagittis tincidunt phasellus elit etiam cursus orci in. Id sed montes.
Lorem ipsum dolor sit amet, consectetur adipiscing elit id venenatis pretium risus euismod dictum egestas orci netus feugiat ut eestas ut sagittis tincidunt phasellus elit etiam cursus orci in. Id sed montes.
Lorem ipsum dolor sit amet, consectetur adipiscing elit id venenatis pretium risus euismod dictum egestas orci netus feugiat ut eestas ut sagittis tincidunt phasellus elit etiam cursus orci in. Id sed montes.
Lorem ipsum dolor sit amet, consectetur adipiscing elit id venenatis pretium risus euismod dictum egestas orci netus feugiat ut eestas ut sagittis tincidunt phasellus elit etiam cursus orci in. Id sed montes.
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Lorem ipsum dolor sit amet, consectetur adipiscing elit id venenatis pretium risus euismod dictum egestas orci netus feugiat ut eestas ut sagittis tincidunt phasellus elit etiam cursus orci in. Id sed montes.
Bis Ende 2025 versorgte sich das Stammzelllabor über einzelne Speisetanks, die in eine Stickstoffleitung einspeisten. Die Probenlagerbehälter füllten bereits automatisch nach, aber nur so lange, wie aus den Speisetanks flüssiger Stickstoff kam. Zum Nachfüllen mussten die Kannen quer durch die Uniklinik transportiert werden.
Das funktionierte, kostete aber regelmäßig Personalzeit und band die Sicherheit der Proben an einen manuellen Transportvorgang. Mit sieben Behältern war die Anlage zudem am Ende ihrer Kapazität, und die Technik war in die Jahre gekommen. Für den Neubau schrieb die Uniklinik RWTH Aachen die kryogene Infrastruktur öffentlich aus.
An automatic liquid nitrogen supply system connects the central storage outside the building to the individual cryo-containers in the laboratory. The nitrogen is transported via vacuum-insulated lines and provided automatically based on the demand of the connected consumers.
The entire system essentially consists of four coordinated areas.
A large-volume outdoor tank serves as the central supply source. It is filled by the gas supplier and provides the necessary liquid nitrogen for the connected laboratory and cryo areas. The required tank size depends on factors such as consumption, the number of cryo-containers, desired delivery intervals, and potential future expansions.
From the outdoor tank, the liquid nitrogen reaches the individual points of use via a permanently installed piping system. The double-walled and vacuum-insulated lines limit heat ingress during transport. This reduces evaporation losses and allows the liquid nitrogen to be distributed efficiently, even over long distances.
Even with high-performance insulation, a portion of the nitrogen can evaporate during transport. This creates a mixture of gaseous and liquid nitrogen in the line. Phase separators vent the gas portion in a controlled manner, allowing the liquid phase to be delivered more consistently to the connected consumers.
The FMCS – Filling Management Control System coordinates the automatic supply of connected cryo-containers. It manages the designated filling sequences and provides relevant system information via a touchscreen interface.
When a cryo-container requires liquid nitrogen, the filling process is triggered automatically and monitored by the system. The exact scope of functions is tailored to the containers used and the facility's requirements.
Up to 20 clones per month
Business, Technology
1 User
3 months
3 months
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Up to 20 clones per month
Business, Technology
1 User
3 months
3 months
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Up to 20 clones per month
Business, Technology
1 User
3 months
3 months
-
FMCS Touch (Filling Management Control System) ist die zentrale Steuerung. Sie koordiniert alle 13 Nachfüllautomatiken, überwacht Füllstände und Drücke an Außentank, Zwischenspeicher und Vakuumleitung, steuert die Vorkühlung und sperrt die Anlage im Fehlerfall.
Biolog® ist die hauseigene Überwachungssoftware von Consarctic® und läuft auf einem PC im Labor. Sie protokolliert Temperaturen, Füllstände und Ereignisse jedes einzelnen Probenlagerbehälters — die Grundlage für die GMP-Nachweisführung.
Kurz gesagt: FMCS Touch beantwortet „Läuft die Anlage sicher?", Biolog® beantwortet „Was ist mit diesem Behälter wann passiert?"
An automatic supply system is particularly well-suited for biobanks, IVF centers, stem cell banks, research laboratories, and pharmaceutical or biotechnology companies that manage multiple cryogenic containers requiring regular refilling. Whether automation is the right choice depends on factors such as the number of units, nitrogen consumption, current staffing requirements, and plans for expanding the cryo-storage facility .
Retrofitting is possible in many facilities. To determine this, we examine the existing cryogenic containers, their connections, potential line routing, and the spatial requirements.
Based on this, Consarctic can assess which components can continue to be used and what technical adjustments are necessary for the automatic liquid nitrogen supply.
The Filling Management Control System handles the central coordination of automatic filling. It processes information from connected consumers and manages the designated filling sequences.
Furthermore, the system provides relevant facility information via a touchscreen interface. The specific functions depend on the respective configuration.
Vacuum-insulated lines limit heat ingress during transport. This results in less liquid nitrogen evaporation compared to less efficient insulation systems.
However, actual losses depend on several factors, such as line length, pipe diameter, operating pressure, frequency of withdrawal, and the overall system design. A reliable assessment is therefore only possible based on the specific installation.
The necessary measures depend on the size of the facility, the nitrogen quantities involved, room volume, ventilation, and potential incident scenarios.
During the planning phase, factors such as outdoor tank placement, shut-off devices, ventilation, oxygen monitoring, alarm systems, and operational emergency procedures must be taken into account. The specific safety concept is coordinated on a project-by-project basis with the operator and the relevant specialist planners.
Der Preis hängt von Behälterzahl, Leitungslänge, Größe des Außentanks und den Sicherheitsanforderungen des Gebäudes ab — eine Anlage dieser Größenordnung wird immer individuell geplant. Consarctic® erstellt nach einer Bestandsaufnahme vor Ort ein konkretes Angebot inklusive Qualifizierung und Wartung.
Consarctic develops supply systems tailored to your spatial, technical, and operational requirements. Our range of services extends from initial needs analysis and planning to outdoor tanks, vacuum lines, and FMCS control, all the way to installation and long-term maintenance. Provide Consarctic with the key data for your facility. Based on this, we can determine how to implement a safe, efficient, and scalable LN₂ supply for your cryogenic containers.